This can be a specific area near where you live, or just general building, such as "Department Store". Give reasons too.
My personal opinion is, if at all possible, get the hell outta' dodge. The farther from urban centers, the farther from all your newly reanimated neighbors. Rural areas have great survivability, not nearly as likely to get "cleansed", and, best of all, lots of NRA nuts.
If stuck in the urban area, try and find a building that is easily closed off with a large roof. Allows for farming and more living area, as well as chopper evac (if the military is feeling nice today).